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Close-Up of Virus Could Ease HIV Vaccine Research

Source: Los Angeles Times

By: Mohan, Geoffrey

10/31/2013

Scientists say that molecular images of a protein spike that enables HIV to invade human immune cells could aid in the search for a vaccine against the deadly virus. “In order to develop a vaccine, you have to understand what bits on that very important trimeric protein can be recognized by broadly neutralizing antibodies,” said Bridget Carragher, a Scripps Research Institute cell biologist who was part of the research team. “And in order to understand that, you need to understand what the structure of the thing looks like.” The findings are reported in two papers in the journal Science.



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