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Effect of Influenza Vaccination in the First Trimester of Pregnancy
Source: Obstetrics & Gynecology | Vol:Vol. 120 | Page: 532
By: Sheffield, Jeanne S. ; Greer, Laura G. ; Rogers, Vanessa L.
09/01/2012
Researchers conducted a five-year, retrospective cohort study of 10,225 pregnant women who received the seasonal trivalent inactive influenza vaccine and compared their delivery and neonatal outcomes with those of women who were not vaccinated. They found that the women who were vaccinated antepartum were much older with higher parity than the unvaccinated women. Moreover, they concluded that first-trimester vaccination did not increase major malformation rates, and the vaccinated group experienced lower rates of stillbirth, neonatal death, and premature delivery than the unvaccinated group.
