Immunization Newsbriefs
Link to Main Page
About NNiiParentsHealthcare ProfessionalsPolicy MakersPressroomPartners
Resources: Newsbriefs
Read Current Issue Online
Search Newsbriefs Archives
Subscribe to Email Online
Unsubscribe from Email Online

Vaccine Info Database

Search the Site

Send Your Feedbck
Read Current NewsbriefsBack

Prevention of Meningococcal Serogroup B Infections in Children: A Protein-Based Vaccine Induces Immunologic Memory
Journal of Infectious Disease Online; 98
De Kleijn, Ester D.; De Groot, Ronald; Lafeber, Arianne B.


Dutch researchers studied immunologic memory against meningococci two and a half years after 177 children received either the hexavalent meningococcal outer membrane vessicle (OMV) vaccine or hepatitis B vaccine. The children were revaccinated with monovalent P1.7(h),4 meningococcal OMV vaccine. According to the authors, the findings reflect the presence of immunologic memory in toddlers and school-aged children previously given three hexavalent meningococcal vaccinations. The researchers concluded that "booster vaccination with monovalent P1.7(h),4 meningococcal OMV vaccine induces a significant increase in [serum bactericidal antibodies] against serosubtype P1.7(h),4 and cross-reactivity against other serosubtypes in the hexavalent vaccine."

© Copyright National Network for Immunization Information. The information contained in the National Network for Immunization Information Web site should not be used as a substitute for the medical care and advice of your health care provider. There may be variations in treatment that your health care provider may recommend based on individual facts and circumstances.